The Australian Phenomics Facility (APF) has become the first combined animal and research service facility to gain ISO/IEC 17025 and ISO/IEC 15189 NATA research and development accreditation in Australia.
“With a commitment to offer the highest quality services the team at the APF have focused their efforts on improving their quality management system across all service areas. We have established a Client Service Charter (CSC) that defines the objectives of the facility, including expected quality and service delivery timeframes, and maintain a commitment to continual improvement and use of current technologies.” Steve Winslade, CEO. The APF is a Government funded facility that sits within the Australian National University, specialising in the creation, characterisation and archiving of mouse models of human disease. The facility offers services and support to academic and commercial research programs both nationally and internationally. The activity of the facility spans two areas, Animal and Research Services with a total of 70 staff, including management, technical and administrative support. What makes the facility unique to other national mouse facilities is the incorporation of “support” services such as genotyping, phenotyping, next generation sequencing, bioinformatics analysis and project management to provide a full spectrum research option.
The facility also offers analysis of human disease cohorts through the phenotyping and genomics services to facilitate the identification of causal mutations and associated phenotypes. To expedite translation of discoveries the APF have recently adopted a new genome editing technology to offer a CRISPR/ Cas9 service, providing mouse models with identical mutations to those carried by an individual or disease cohort. A CRISPR mouse model can be created for any mutation, providing a more targeted, efficient and cost effective option than traditional mutagenesis or knockout approaches.
In addition to our recent NATA accreditation the facility is compliant with legislation governed by the Office of the Gene Technology Registrar (OGTR), ANU Animal Experimentation Ethics Committee (AEEC), Department of Agriculture, Forestry’s and Fisheries (DAFF) and other relevant legislative authorities.